Vogt-小柳原田综合征治疗前后OCT图像分析

Analysis on optical coherence tomography in Vogt-Koyanagi-Harada syndrome before and after therapy

目的:分析Vogt-小柳原田综合征治疗前后光学相干断层扫描(OCT)图像特征。方法:对确诊的Vgot-小柳原田综合征患者17例34眼应用眼底照相及OCT跟踪观察,于激素冲击疗法后的5,15,30d再次行上述检查,观察视网膜结构变化。结果:所有患者均出现视网膜神经上皮层水肿及多灶性局限性大小不等的浆液性视网膜神经上皮脱离,经激素冲击治疗后,视网膜水肿减轻甚至消失,神经上皮脱离腔减小,部分脱离腔消失、视网膜基本复位。结论:OCT可清晰观察Vogt-小柳原田综合征治疗前后视网膜结构变化,对该病的诊断及疗效评估有重要意义。

AIM： To analyze features of optical coherence tomography （ OCT） in Vogt-Koyanagi-Harada syndrome before and after therapy. METHODS：Thirty-four eyes of 17 patients, which were identified as Vogt-Koyanagi-Harada syndrome, were examined with OCT and fundus photography, after the treatment of steroid therapy, the change of retinal structure were observed after 5, 15, 30d. RESULTS： OCT revealed retinal neuroepithelial edema and serous detachment of retinal neuroepithelia and subretinal septa that divided the subretinal space into several compartments all of cases.After steroid therapy, the retinal edema, serous detachment and subretinal septa were improved, even resolved completely. CONCLUSION： OCT can observe retinal structural change of Vogt-Koyanagi-Harada syndrome before and after therapy, it is vital for diagnosis and treatment evaluation of the disease.