原发性胆汁性肝硬化相关抗体检测研究进展

Progress of studies on detection of primary biliary cirrhosis associated antibody

原发性胆汁性肝硬化是一种病因不明,以肝内中、小胆管非化脓性、进行性、炎症损伤为特征的慢性胆汁淤积性自身免疫性疾病。早期进行相关抗体检测非常重要,本文对原发性胆汁性肝硬化的相关抗体,如线粒体抗体、抗核抗体、着丝点抗体等进行了综述,并分析了各自在检测中的作用。

Primary biliary cirrhosis （PBC） is an autoimmune disease of the liver, marked by the slow progressive destruction of the small bile ducts of the liver, with the intralobular ducts affected early in the disease. to cure. The detection of associated antibodies in the early stage is very important. In this paper, we reviewed all the antibodies in PBC detection, including anti-mitochondrial antibody, antinuclear antibody, anticentromere antibodies and so forth.