摘要
目的:探讨生物电阻抗原理(bioelectrical impedance analysis, BIA)在评价慢性肾脏病儿童营养方面的临床应用价值。方法选取2009年至2011年期间就诊于北京儿童医院肾脏内科的单中心慢性肾脏病(chronic kid-ney disease, CKD)患儿57例(CKD组),同时选择健康儿童54例作为正常对照组。利用生物电阻抗原理对儿童进行人体成分(主要包括蛋白质、脂肪含量的测定)的评估及比较。结果 CKD组蛋白质相对含量为(14.72±2.44)%,正常对照组为(18.10±3.91)%,两组间差异有统计学意义(t=2.61,P=0.000);CKD组脂肪相对含量为(24.31±12.52)%,显著高于正常对照组的(16.1±17.34)%,差异有统计学意义(t=3.89,P=0.000);CKD1~2期患儿蛋白质相对含量为(34.57±7.39)%,CKD3~5期患儿含量为(41.08±5.53)%,两者比较差异有统计学意义(t=3.749,P=0.000);CKD1~2期患儿相对脂肪含量为(28.73±12.50)%,CKD3~5期患儿含量为(16.13±7.52)%,其差异有统计学意义(t=-4.745,P=0.000)。 CKD组中47例(82.45%)处于营养成分失衡状态;在身高别体重提示营养状况良好的32例CKD患儿中25例(78.12%)存在营养成分不均衡。结论 CKD患儿存在蛋白质、脂肪等人体成分不均衡状态,个体化、针对性的营养管理对CKD患儿的营养状况改善有一定帮助。生物电阻抗原理对于评价CKD患儿营养状况有一定的临床应用价值。
Objectives To evaluate the nutritional status of children with chronic kidney disease(CKD) by bioelec-trical impedance analysis (BIA) and explore the value of BIA in assessing the nutritional status of children with CKD. Methods Fifty-seven patients with CKD who were hospitalized in Beijing Children's Hospital from 2009 to the end of 2011 were enrolled in this study. They were classified to be stages 1-5 according to the recommendation by the National Kidney Foundation Disease Outcomes Quality Initiative. (NKF-KDOQI). Fifty-four healthy children were chosen as the control group. Body composition such as protein and fat were measured by bioelectrical impedance analysis in 57 patients and 54 controls. The results of the nutritional assessment by the two ways were analyzed. Statistical analysis were carried out by SPSS16.0. Results Less protein (t= 2.61, P< 0.05), but more adipose (t= 3.89, P< 0.05) were found in CKD children. Compared with the children of CKD classified as CKD1-2, the children classified as CKD3-5 had relatively more protein(t=3.749, P<0.05), but relatively less adipose (t=-4.745, P<0.05). Forty-seven cases(82.45%) of 57 CKD chil-dren were in the imbalance nutritional status assessed by body composition. In those (32case) who were normal assessed by the methods recommended by American Academy of Pediatrics, 25 (78.12%) patients were in nutrition disorder. Con-clusion Children with CKD are in the imbalanced nutritional status. BIA is helpful in evaluating the nutritional status of CKD children.
出处
《北京医学》
CAS
2014年第4期257-260,共4页
Beijing Medical Journal