动脉粥样硬化的分子磁共振成像

Molecular magnetic resonance imaging of atherosclerosis

动脉粥样硬化是一种慢性炎性血管性疾病，从早期的脂纹发展至晚期具有高度破裂倾向的不稳定斑块，每一步都有许多细胞和分子事件的参与。随着靶向探针技术的发展，分子磁共振成像技术有望在不久的将来彻底改变人们对动脉粥样硬化的处理策略。近年来，已涌现出许多理想的靶向斑块各种成分的分子探针。文章综述了动脉粥样硬化的分子磁共振成像技术及其应用。

Atherosclerosis is a chronic inflammatory vascular disease developing from early fatty streaks to highly rupture-prone unstable plaques. Many cellular and molecular events are involved in each step. With the development of targeting probe technology, molecular magnetic resonance imaging techniques are expected to revolutionize the treatment strategies of atherosclerosis in the near future. Many desirable molecular probes targeting various components of plaque have emerged in recent years. This article reviews the molecular magnetic resonance imaging techniques of atherosclerosis and their application.