期刊文献+

干燥方法对控制释放LGG的影响

Effect of drying conditions on controlled release of LGG
下载PDF
导出
摘要 采用果胶钙交联载体微球包埋鼠李糖乳杆菌GG(LGG),考察不同干燥方法对储藏存活率和载体释放性能的影响.结果表明:应用冷冻干燥和自然风干两种干燥方法干燥后的果胶钙微球在胃肠上部都未降解,在结肠被降解并释放LGG;再与未经干燥处的载体微球相比,得出冷冻干燥法是长期保存含有LGG微球的最好方法. The LGG was encapsulated in pectin/Ca2+hydrogel beads, and the effects of the different drying conditions on survivability of LGG and its release from the beads were investigated. The results indicate that the freeze dried and air dried beads remained intact in the upper gastrointestinal tract and were degraded and released LGG in the colon. However, freeze dried beads increased survivability of LGG in comparison with air dried and non-dried beads.
作者 李冉 张宇峰
出处 《天津工业大学学报》 CAS 北大核心 2014年第1期32-35,共4页 Journal of Tiangong University
基金 国家自然科学基金项目(21274108) 国家高技术研究发展计划(863计划 2012AA03A602)
关键词 干燥 果胶 控制释放 冷冻干燥 LGG drying pectin LGG controlled release freeze dry
  • 相关文献

参考文献11

  • 1YAN F,POLK D B. Probiotics:Progress toward novel therapies for intestinal diseases[J]. Curr Opin Gastroenterol,2010,26(2):95-101.
  • 2YAN F,POLK D B. Probiotics as functional food in the treatment of diarrhea[J]. Curr Opin Clin Nutr Metab Care,2006,9(6):717-721.
  • 3钱程,霍贵成,马微.鼠李糖乳杆菌(LGG)的功能特性及其应用前景[J].食品科技,2005,30(9):94-98. 被引量:28
  • 4宋士良.益生菌在食品中应用状况及安全性评估[J].食品科技,2009,34(7):22-26. 被引量:12
  • 5YAN F,POLK D B. Probiotic bacterium prevents cytokine-induced apoptosis in intestinal epithelial cells[J]. J Biol Chem,2002,277(52):50959-50965.
  • 6YAN F,CAO H,COVER T L,et al. Colon-specific deliveryof a probiotic-derived soluble protein ameliorates intestinal in原flammation in mice through an EGFR-dependent mechanism[J]. J Clin Invest,2011,121:2242-2253.
  • 7LIU L S,FISHMAN M L,KOST J,et al. Pectin-based systems for colon-specific drug delivery via oral route [J]. Biomaterials,2003,24(19):3333-3343.
  • 8LIU L S,FISHMAN M L,HICKS K B,et al. Interaction ofvarious pectin formulations with porcine colonic tissues [J].Biomaterials,2005,26:5907-5916.
  • 9LIU L S,CHEN G,FISHMAN M L,et al. Pectin gel vehiclesfor controlled fragrance delivery[J]. Drug Delivery,2005,12:149-157.
  • 10SINHA V R,KUMIRA R. Polysaccharides in colon-specificdrug delivery[J]. Int J Pharm,2001,224:19-38.

二级参考文献23

共引文献38

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部