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Bmi-1在人类实体肿瘤诊治中的相关研究进展

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摘要 B细胞特性莫洛尼小鼠白血病毒插入位点1（B cell-specific MLV integration site-1,Bmi-1）在近期的研究中发现高表达于多种人类肿瘤,并参与肿瘤的恶性表型维持和恶性转化,具有癌基因性质,与肿瘤的分化,分期密切相关,是预后的独立因子.它在人类实体肿瘤中的表达是一个具有巨大潜力的标志,为患者的早期诊断、生存率预测和肿瘤的治疗提供了一个有巨大潜能的途径.鉴于Bmi-1在人类肿瘤中的重要作用,本文对其研究进展作一综述.
作者 秦悦(综述) 柳建军(审校)
机构地区 湛江 广东医学院附属医院泌尿外科
出处 《国际泌尿系统杂志》 2014年第2期239-244,共6页 International Journal of Urology and Nephrology
关键词 肿瘤 基因
分类号 R73 [医药卫生—肿瘤]
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参考文献58

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国际泌尿系统杂志
2014年 第2期

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