深圳市龙岗区小儿细菌病原学感染状况

Survey of Bacterial Etiology of Infection among Young Children at Longgang District of Shenzhen City

目的针对小儿腹泻发病特点和流行病学特征,探讨控制和减少小儿感染性腹泻的措施及预防对策。方法选择2010年1月至2012年12月在深圳市龙岗区人民医院就诊,每日排便≥3次的小儿,作为研究对象,在患儿未使用抗菌药物之前进行大便细菌病原学检验并进行描述性统计分析。结果 539例小儿感染性腹泻病例中男女比例为1.44∶1,共检出101株病原菌,总分离率18.73%(101/539)。居前三位的是致病性大肠埃希菌(EPEC)37.62%(38/101)、产毒性大肠埃希菌(ETEC)27.72%(28/101)、沙门菌17.82%(18/101)。3岁以下小儿检出病原菌最多占85.15%(86/101);以秋季腹泻最多占52.48%(53/101)。结论龙岗区小儿感染性腹泻以EPEC和ETEC感染为主。

Objective To analyze characteristics of the disease and epidemiological characteristics for children with diarrhea,and explore measures to control and reduce infectious diarrhea in children and the preventive measures.Methods In Jan.2010 to Dec.2012 in Long,gang District People＇s Hospital,children patients having defecation more than 3 times a day were collected for the study,the examination of pathogenic bacteria was performed in the fecal specimens before antimicrobial therapy,and the results were analyzed with descriptive statistics.Results Among 539 specimens,with the male to female ratio of 1.44∶1,101 strains of pathogenic bacteria were isolated with the positive rate of 18.73% （101/539）.The top three pathogenic bacteria were pathogenic Escherichia coli （EPEC） accounting for 37.62% （38/101）,enterotoxigenic Escherichia coli （ETEC） accounting for 27.72% （28/101）,Salmonella bacillus accounting for 17.82% （18/101）.Pathogens detected in children under 3 years of age accounted for 85.15% （86/101） ;autumn diarrhea accounted for 52.48% （53/101）.Conclusion The Main infections of diarrhea are EPEC and ETEC in children at Longgang District.