肺结核与肺癌相关性的临床研究

Clinical study on the relationship between pulmonary tuberculosis and lung cancer

肺结核发生发展主要是炎症介质反应的结果,而肺癌致病机制复杂,涉及多基因多分子的参与.肺结核患者的免疫异常、抗结核药物、瘢痕修复、慢性炎症刺激以及结核菌素的毒力均与肺癌的发生密切相关.肺结核合并肺癌患者的治疗包括联合化疗、手术以及放疗等有限手段.

The pathogenesis of pulmonary tuberculosis involves inflammatory mediators reaction, and the pathogenesis of lung cancer is complex, involving multiple genes and molecules. The lung cancer has some relevance with pulmonary tuberculosis in terms of immune abnormalities, antituberculosis drugs, scar repair, chronic inflammation and tuberculin virulence. The treatment of tuberculosis patients with lung cancer is limited to chemotherapy, surgery and radiotherapy.