月经紊乱患者血清性激素及甲状腺功能的相关分析

Analysis of the Correlation Between Serum Sex Hormones and Thyroid Function in Patients with Menstrual Disorder

【目的】探讨月经紊乱患者血清性激素与甲状腺功能的相关性。【方法】选取200例月经紊乱患者（观察组）和200例健康体检者（对照组），检测两组性激素六项及游离三碘甲状腺原氨酸（FT3）、游离甲状腺素（FT4）、促甲状腺激素（TSH）三项，分析甲状腺功能与月经紊乱的相关性。【结果】观察组与对照组 FT3、FT4、TSH比较无显著性差异（ P ＞0．05），但观察组与对照组甲状腺功能减退（甲减）的发生率比较有统计学差异（ P＜0．05）；观察组甲减以月经稀发为主，其次为月经过多；亚临床甲减以月经稀发为主；甲状腺功能亢进（甲亢）以月经过少为主；亚临床甲亢以月经过少和过多为主。【结论】甲状腺功能的紊乱能够引起女性月经失调，甲状腺功能的检测对月经紊乱有一定的指导意义。

[Objective] To explore the relationship between serum sex hormone and thyroid function in patients with menstrual disorder .[Methods] Totally 200 patients with menstrual disorder （observation group） and 200 healthy subjects （control group） were chosen .Six sex hormones and FT3 ,FT4 and TSH in two groups were measured .The correlation between serum sex hormones and thyroid function were analyzed .[Results] There was no significant difference in FT 3 , FT4 and TSH between observation group and control group （ P〈0 .05） ,while there was significant difference in the inci-dence rate of hypothyroidism between observation group and control group （ P〈0 .05） .The major symptom of hypothy-roidism was oligomenorrhea ,and the second was hypermenorrhea .The major symptom of subclinical hypothyroidism was oligomenorrhea ,and that of hyperthyroidism was hypomenorrhea .The major symptoms of subclinical hyperthyroidism were hypomenorrhea and hypermenorrhea .[Conclusion] Thyroid dysfunction can cause menstrual disorder in women . The detection of thyroid function is of the significance for menstrual disorder .