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顶、颞、枕叶白质在帕金森患者认知障碍发病中的测定价值 被引量:3

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摘要 目的探讨顶白质,颞白质,枕白质在帕金森患者认知障碍发病中的测定价值,为帕金森患者认知障碍的防治提供科学理论。方法选取我院收治的帕金森病患者72例,并依照认知障碍评定量表(MoCA)判定为认知障碍的36例帕金森患者为帕金森认知障碍组(PDD组),判定为无认知障碍的36例帕金森患者为帕金森未发认知障碍组(PD-CogNL组),观察2组顶白质,颞白质、枕白质的FA(部分各异性)值。结果 PPD组颞叶白质、枕叶白质FA值均低于PD-CogNL组,差异均有统计学意义(P<0.05)。2组顶叶白质FA值比较差异无统计学意义(P>0.05)。结论顶白质结构变化与帕金森患者认知障碍无显著相关,而颞白质、枕白质结构变化与帕金森患者认知障碍发病具有显著相关性,因此颞白质和枕白质很可能能作为测定帕金森患者是否并发认知障碍的参照指标,值的临床进一步探讨。
出处 《临床合理用药杂志》 2014年第10期131-132,共2页 Chinese Journal of Clinical Rational Drug Use
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参考文献4

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同被引文献16

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  • 9陈伶,刘卫国,赵燕燕,华平,王阳,张宁.蒙特利尔认知评估量表在帕金森病认知障碍患者中的应用价值[J].中华神经科杂志,2011,44(3):200-202. 被引量:29
  • 10李振光,于占彩,王道珍,鞠卫萍,詹霞,蒋东晓,于永鹏,丛艳斌.帕金森病患者血浆磷脂含量变化及其与轻度认知功能障碍的关系[J].国际老年医学杂志,2013,34(3):97-101. 被引量:5

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