抗生素降阶梯治疗小儿重症肺炎的效果观察

Effect observation of de-escalation of antibiotics treating pediatric severe pneumonia

目的分析抗生素降阶梯治疗小儿重症肺炎的临床效果。方法选取本院2012年10月~2013年10月收治的60例小儿重症肺炎患者为研究对象，将其随机分为观察组与对照组，每组各30例。对照组采用常规治疗模式．观察组采用抗生素降阶梯治疗，对两组患者的临床效果进行分析对比。结果观察组中显效20例（66．67％），有效7例（23．33％）．无效3例（10．0％），总有效率为90．0％；对照组中显效15例（50．0％），有效6例（20．0％），无效9例（30．0％），总有效率为70．O％，观察组的显效率、总有效率显著高于对照组（P〈O．05）。结论抗生素降阶梯治疗小儿重症肺炎具有良好的临床效果，值得临床推广应用。

Objective To analyze the clinical effect of de-escalation of antibiotics treating pediatric severe pneumonia. Methods 60 children with severe pneumonia admitted into our hospital from October 2012 to October 2013 were se- lected as research objects and they were randomly divided into the observation group （n=30） and the control group （n=30）. In the control group,conventional therapy was provided,while in the observation group,the de-escalation of an- tibiotics therapy was applied.The clinical effect in both groups was compared and analyzed. Results In the observation group,the excellent,effective and ineffective cases were 20 （66.67%）,7 （23.33%）,and 3 （10.0%） respectively,the total ef- fective rate was 90.0%.In the control group,the excellent, effective, and ineffective cases were 15 （50.0%）,6 （20.0%）,and 9 （30.0%）,the total effective rate was 70.0%.The success rate and the total effective rate in the observation group were higher than those in the control group （P〈0.05）. Conclusion The de-escalation of antibiotics treating pediatric severe pneumonia can obtain a great clinical effect,and it is worthy of clinical promotion and application.