肺癌T分期与淋巴结转移关系

Relationship between the T staging of the seventh edition and lymph nodes metastasis of lung cancer

目的 探讨新版（第7版）肺癌TNM分期中T新分级与淋巴结转移的关系.方法 对513例非小细胞肺癌原发肿瘤大小及淋巴结转移进行回顾性分析,探讨不同大小原发肿瘤中淋巴结转移的情况.结果 肿瘤最大径≤2 cm（T1a）、2 cm＜～≤3 cm（T1b）、3cm＜ ～≤5 cm（T2a）、5cm＜～≤7cm（T2b）、＞7 cm（T3）的淋巴结转移率分别为14.47％、28.89％、37.59％、36.37％、37.89％,T1a与T1b,、T2a、T2b、T3间淋巴结转移率有显著性差异.N1淋巴结转移各组间P＜0.05.N2淋巴结转移例数各组间P＜0.05,T1a与T1b、T2a、T2b间淋巴结转移率比较差异有显著性.T1b与T2a、T2b、T3之间差别有显著性.结论 新版TNM分期中肿瘤大小的新分级与淋巴结转移率有关,其差异主要在N2上;T1a淋巴结转移率低.

Objective The new lung cancer TNM staging for T staging the new grading.The aim of this study was to investigate the relationship between the T staging and grading of the Seventh Edition and lymph node metastasis of lung cancer.Methods In 513 cases of non-small cell lung cancer primary tumor size and lymph node metastasis were analyzed,and explore the situation of different size,lymph node metastasis in primary tumors.To analyse the collected data with SPSS software.Results The total lymph node metastatic rates in tumor diameter biggest ≤2 cm（T1a） 、2 cm ＜ ～ ≤3 cm（T1b） 、3 cm ＜ ～ ≤5 cm （T2a） 、5 cm ＜ ～ ≤7 cm（T2b） 、＞ 7 cm（T3） were 14.47％ 、28.89％ 、37.59％ 、36.37％ 、37.89％.The lymph node metastatic rate of T1a was significantly different,compared with T1b 、T2a 、T2b and T3,respectively.There were no differences between every two groups of T1b,T2a,T2b and T3.The N1 metastaic rates of T1a 、T1b 、T2a 、T2b 、T3 were compared by chi-square（P ＜0.05）,The lymph node metastatic rates of T1a and T2a （P =0.001）,T1a and T2b （P =0.024）.The N2 metastaic rates of T1a 、T1b 、T2a 、T2b 、T3 were compared by chi-square（P ＜0.05）,The lymph node metastatic rate of T 1 a was significantly different,compared with T1b 、T2a and T2b,respectively.The lymph node metastatic rate of T1 b was significantly different,compared with T2a 、T2b and T3,respectively.Conclusion The new T staging of tumor the size of the new classification is associated with lymph node metastasis rate,especially in N2.low T la lymph node metastasis rate.