摘要
已有研究提示微小RNA(miRNA)参与了多种肿瘤包括胃癌的发生、发展,幽门螺杆菌(Hp)与胃癌发生、发展关系密切。近期研究表明Hp可能通过miRNA途径促进胃癌的发生、发展。本文就胃癌相关miRNA,尤其是Hp感染相关miRNA分子及其作用机制作一综述。
microRNA is thought to play an important role in the pathogenesis and development of many tumors including gastric cancer. Helicobacter pylori （Hp） is a key factor in the pathogenesis of gastric cancer. Recent data have shown that Hp may lead to gastric cancer through microRNA pathway. This article reviewed the role of gastric cancer- related miRNA especially the Hp-related miRNA in genesis of gastric cancer.
出处
《胃肠病学》
2014年第3期185-187,共3页
Chinese Journal of Gastroenterology
基金
兰州军区卫生科研基金(CXA13JA14)资助
关键词
幽门螺杆菌
胃肿瘤
微RNAS
Helicobacter pylori
Stomach Neoplasms
MicroRNAs
