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畸精症与正常男性精子完整性DNA检测的对照研究 被引量:1

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摘要 随着全球对男性生殖健康问题呼声的日益高涨,我国对男性不孕不育的关注程度也空前火热。过去精子形态分析被认为是精液质量评估的重要指标,也被认为是辅助生殖技术(assistedreproductivetechniques,ART)最重要的参考和预测标准。但是现代科学研究发现15%男性的不孕不育并非精子形态异常造成,而是与精子核的异常有关。精子核异常主要包括微缺失、染色质结构异常、非整倍体和DNA链断裂,但过去常规的检测手段不能很好的反映这些发生DNA水平上的异常,因此有必要探讨和完善DNA完整性检测的临床应用。
出处 《新疆医学》 2013年第12期64-65,79,共3页 Xinjiang Medical Journal
基金 国家临床重点专科建设项目
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