抗感利咽喷雾剂雾化吸入治疗小儿手足口病的疗效观察

Clinical Observation of Effects of Kangganliyan Spray Aerosol on Children with Hand-foot-mouth Disease

目的:观察抗感利咽喷雾剂雾化吸入治疗小儿手足口病的临床疗效。方法:80例手足口病患儿随机分成两组,对照组(n=40例)仅给予利巴韦林静脉滴注治疗;治疗组(n=40例)在此基础上加用抗感利咽喷雾剂雾化吸入治疗。两组疗程均为5天。观察和比较两组疗效和各项临床症状体征改善情况。结果:治疗组总有效率(95%)明显高于对照组(77.5%)(P<0.05);治疗组退热时间、口腔疱疹消退时间和食欲改善时间均短于对照组(P<0.01)。结论:抗感利咽喷雾剂雾化吸入治疗小儿手足口病疗效显著,可明显改善临床症状体征,值得临床推广应用。

Objective：To observe the clinical effects of Kangganliyan Spray on children with hand-foot-mouth disease. Methods：80 cases of children with Hand-foot-mouth disease were randomly divided into two groups. The control group （n=40 cases） was given intravenously ribavirin. In addition to ribavirin, the experimental group was inhaled with aerosol of Kangganliyan. The course of treatment in both groups was 5 days. The improvement of clinical symptoms and signs in two groups were observed. Results：The total effective rate of the treatment in the experiment group was 95%, which was 77.5%higher than that of the control group （P〈0.05）. The defervescence time, relieving time of oral herpes and appetite improved time of the experimental group were less than those of the control group （P〈0.01）. Conclusion：Aerosol inhalation with Kangganliyan Spray can significantly improve the clinical symptoms and signs of children with hand-foot-and-mouth disease and worthy of promotion in clinic practice.