米诺环素软膏与碘甘油治疗急性智齿冠周炎的效果比较

Minocycline Ointment and Iodine Glycerin in Treatment of Acute Pericoronitis of Wisdom Tooth Effect

目的:探讨米诺环素软膏治疗急性智齿冠周炎的临床价值。方法:160例急性智齿冠周炎患者随机分观察组和对照组各80例,先用生理盐水和3%双氧水交替冲洗冠周盲袋,冲洗干净后,擦干,隔湿,观察组将米诺环素软膏轻轻注入冠周及盲袋底,至袋底有软膏溢出,共1次;对照组碘甘油灌注,将药液放置于牙周袋口,再用口腔探针将药液流逐渐导入到牙周袋内,隔日一次。结果:观察组疼痛缓解时间短于对照组(P<0.05),治疗5天以后观察组总有效率高与对照组(P<0.05)。对照组3例因碘过敏及碘制剂对牙龈刺激性退出治疗,观察组无不良反应发生。结论:盐酸米诺环素能在局部维持较高的浓度,可明显改善临床症状,提高临床效果,不良反应小。

Objective：To explore the clinical value of minocycline ointment treatment acute pericoronitis. Methods：160 cases of acute pericoronitis were randomly divided into observation group and control group with each 80 cases, with saline and 3%hydrogen peroxide alternately flushing Pericoronal blind bag, wash clean, dry, wet insulation, the observation group will minocycline ointment gently injection Pericoronal and blind to the bottom of the bag at the bottom of the bag, soft paste overflow, a total of 1 times;the control group iodine glycerin filling, liquid will be placed in the periodontal pocket, then the oral probe liquid flow gradually into the periodontal pocket, once every other day. Results：The observation group pain relief time shorter than the control group （P〈0.05）, after treatment 5 days the observation group total effective rate is high and the control group （P〈0.05）. Control group 3 cases due allergy to iodine and iodine preparations on gingival irritation from the treatment, the observation group had no adverse reactions. Conclusion：Minocycline hydrochloride can maintain high concentration in the local, can significantly improve the clinical symptoms, improve clinical efficacy, and adverse reactions.