舒巴坦钠/头孢哌酮钠治疗小儿急性菌痢的疗效观察

Efficacy of Sulbactam and Cefoperazone in the Treatment of Children with Acute Dysentery

目的:探讨舒巴坦钠/头孢哌酮治疗小儿急性菌痢患者的临床疗效。方法:选择我院收治的102例急性菌痢性患儿的临床资料,其中,观察组54例患者采用舒巴坦钠/头孢哌酮药物进行临床治疗,对照组48例患者采用头孢噻肟钠治疗,对比两组患者的临床效果。结果:治疗后,观察组患者的临床总有效率为98.15%,明显高于对照组患者,且差异具有显著统计学意义(P<0.05),而且,观察组患者的发热、腹泻、大便培养等临床症状和体征的消失时间均明显优于对照组患者,有统计学差异(P<0.05)。结论:舒巴坦钠/头孢哌酮治疗小儿急性菌痢具有较佳的效果,值得临床广泛推广和应用。

Objective：To investigate the clinical efficacy of sulbactam and cefoperazone in the treatment of children with acute dysentery. Methods： 102 acute dysentery children were divided into two groups, including the observation group of 54 patients with sulbactam/cefoperazone and control group of 48 patients with cefotaxime, and the clinical effect of two groups were compared. Results：After treatment, the total effective rate of observation group was 98.15%, significantly higher than control group patients, and the difference was statistically significant （P〈0.05）, and the observation group with fever, diarrhea, stool culture, etc. the disappearance of clinical symptoms and signs were significantly better than the control group of patients, and the differences were statistically significant （P〈0.05）. Conclusion：Sulbactam and cefoperazone in the treatment of children with acute dysentery has good results, and it is worthy of wider promotion and application.