卡前列素氨丁三醇与缩宫素在产后出血治疗中的疗效对比分析

Comparison of the Effectiveness of Carboprost Tromethamine and Oxytocin for the Prevention of Postpartum Hemorrhage

目的:对比分析卡前列素氨丁三醇与缩宫素在产后出血治疗中的疗效。方法:将280例有产后出血高危因素的产妇在胎儿娩出后分别运用卡前列素氨丁三醇及缩宫素治疗,观察两组产妇出血发生率、不良反应发生率及产后2h、24h出血量,并进行比较。结果:卡前列素氨丁三醇产后出血发生率、及产后2h、24h出血量均较缩宫素组低,两组比较具有统计学差异(P<0.05),不良反应发生率两组无统计学差异(P>0.05)。结论:早期使用卡前列素氨丁三醇在防治产后出血较缩宫素具有更显著的效果,值得临床运用和推广。

Objective：To compare of carboprost tromethamine and oxytocin in the treatment of postpartum hemorrhage. Methods：280 patients with high risk factors of maternal postpartum hemorrhage were treated by carboprost tromethamine and oxytocin after fetal delivery. the rate of hemorrhage, the incidence of adverse reaction of 2h, 24h and postpartum hemorrhage were observed and compared in the two groups. Results：The rate of postpartum hemorrhage, 2h and 24h postpartum hemorrhage volume in carboprost tromethamine group was significant difference than oxytocin group. There were significant statistical difference between the two groups （P〈0.05）, the incidence of adverse reaction of two groups showed no statistical difference （P〉0.05）. Conclusion：The early use of carboprost tromethamine in the prevention of postpartum hemorrhage had more significant effect than oxytocin, worthy of clinical application and popularization.