外周血退化细胞对急性上呼吸道感染诊断的临床意义

The clinical significance of peripheral blood senile cell in acute upper respiratory infection diagnosis

目的探讨外周血退化细胞阳性率和占白细胞平均比例对判定急性上呼吸道感染患者病情程度的临床意义。方法选择2961例急性上呼吸道感染患者,常规制作薄血片,瑞氏染色,待血片干燥,低倍镜阅片后油镜下进行有核细胞分类计数(将退化细胞计数在内),并仔细观察细胞形态,对计数结果进行统计学分析。结果男女患者退化细胞阳性率比较,差异无统计学意义(x^2=2.95,P>0.05);随体温升高,退化细胞阳性率及占白细胞平均比例均呈上升趋势,且各体温段间比较,差异均有统计学意义(P均<0.05)。各体温段退化细胞阳性率,除了38.1℃~与39.1℃~、38.1℃~与40.1℃~及39.1℃~与40.1℃~间比较差异均无统计学意义外(P均>0.05),其他各体温段间两两比较,差异均有统计学意义(P均<0.005)。占白细胞平均比例各体温段间两两比较,差异均有统计学意义(P均<0.001)。结论急性上呼吸道感染患者随体温升高,其退化细胞阳性率及占白细胞平均比例均呈上升趋势,二者可作为判定急性上呼吸道感染患者病情轻重的指标。

Objective To study the clinical significance of positive rate of peripheral blood senile cell and its average ratio accounted for WBC in acute upper respiratory infection diagnosis. Methods A total of 2961 cases of acute upper respiratory infection patients were collected. Regular production of thin blood films, Wright＇s stain, after the blood films dry, differential cell counting under oil immersion lens, and observing the cell morphology. The results were analyzed statistically. Results There was no statistical significance in the difference of positive rate of senile cell in different gender （x2= 2.95, P〉 0.05）. With the temperature rised, the positive rate of senile cell and its average ratio accounted for WBC showed an upward trend, and there were all had statistical significance in different temperature ranges （Pall〈 0.05）. There were all had statistical significance in the differences of positive rate between each two temperature ranges （Pall 〈 0.005） except 38.1 ℃ -and 39.1 ℃-,38.1℃- and 40.1 ℃-,39.1℃- and 40.1 ℃-（Pall〉 0.05）. There were all had statistical significance in the differences of average ratio accounted for WBC between each two temperature ranges （Pall 〈 0.001 ）. Conclusion With the temperature rised, the positive rate of senile cell and its average ratio accounted for WBC show an upward trend in acute upper respiratory infection patients, they can be the index for diagnosing the pathogenetic condition of acute upper respiratory infection patients.