孕期营养补充剂抗疲劳、耐寒、耐热动物实验观察

Effect of pregnancy nutrition supplement on resistance of fatigue,cold and high temperature in mice

目的:通过抗疲劳、耐寒、耐热实验分析孕期营养补充剂对小鼠机体生命活力的影响。方法:SPF级昆明小鼠随机分为高、中、低剂量和对照共4组,灌胃给药21d后,进行动物实验。结果:负重游泳时间在雌性小鼠的3个剂量组均明显增加(P均<0.05),在雄性小鼠的中、高剂量组明显增加(P<0.05);耐寒时间在雌性小鼠的中、高剂量组明显增加(P<0.01),在雄性小鼠的3个剂量组均明显增加(P<均0.05);耐热时间在雌性和雄性小鼠的中、高剂量组均明显增加(P<0.05)。结论:服用多种维生素、多种矿物质的营养补充剂的小鼠机体活力明显增加,抗疲劳、抗寒和抗热的能力显著提高。

Objective：To explore the effect of pregnancy nutrition supplement on the resistance of fatigue,cold and high temperature in mice.Methods：SPF Kunming mice were randomly divided into 4 groups.Twenty-one days after oral administration,the resistance of fatigue,cold and high temperature were evaluated.Results：The swimming time of female mice were significantly increased in 3 does groups （P all ＜0.05）,and that was significantly increased in the medium-and high-does groups of male mice （P＜0.05）.The survival time of low temperature of female mice were significantly increased in medium-and high-does groups （P ＜0.01）,and that was significantly increased in all 3 does groups of male mice （P all ＜0.05）.The survival time of high temperature of both male and female mice were significantly increased in the medium-and high-does groups （P＜0.05）.Conclusion：Pregnancy nutrition supplement could improve the resistance of fatigue,cold and high temperature in mice.