河北省四地区城市社区老年人轻度认知功能损害的影响因素调查

The related factors to mild cognitive function impairment in community elderly people in 4 areas of Hebei Province

目的 探讨河北省4个地区城市中年龄≥60岁无脑梗死和帕金森病的社区老年人轻度认知功能损害的高危因素.方法 采用多阶段整群随机抽样方法,于2010年1-12月对河北省4个地区年龄≥60岁的老年人进行社会人口学资料和危险因素问卷调查以及MMSE评估.结果 MMSE正常组2 659人,MMSE异常组505人（12人因不配合MMSE评估未纳入统计）.2组在以下方面存在差异：年龄70 ～ 79岁（x2=78.473,OR=2.658,95％ CI：2.129～3.319,P=0.000）和≥80岁（x2 =252.168,OR=8.555,95％CI：6.356～11.516,P =0.000）;受教育年限：1～6年（x2=62.066,OR=0.329,95％CI：0.248 ～ 0.437,P=0.000）,7 ～ 12年（x2=52.634,OR=0.395,95％ CI：0.305～0.510,P=0.000）,＞12年（x2=96.162,OR=0.126,95％ CI：0.080 ～0.200,P=0.000）;丧偶（x2 =51.710,OR =2.263,95％ CI：1.804～2.839,P=0.000）或其他婚姻状况（x2=64.450,OR=3.733,95％ CI：2.654 ～5.251,P =0.000）;独居（x2=27.765,OR=2.135,95％CI：1.601 ～2.847,P=0.000）;从事农业（x2=8.425,OR=1.576,95％ CI：1.157～2.147,P=0.003）,国家机关工作人员（x2 =4.148,OR=0.678,95％CI：0.466～0.987,P=0.049）,无业（x2=8.260,OR=1.701,95％ CI：1.181 ～2.450,P =0.004）;不运动（x2=52.987,OR=2.315,95％CI：1.838 ～2.916,P=0.000）;生活事件：1～2件（x2 =8.220,OR=1.412,95％CI：1.115 ～1.790,P=0.004）,≥3件（x2 =41.109,OR=2.545,95％CI：1.901 ～3.406,P=0.000）;低业余活动（x2=77.530,OR=2.577,95％ CI：2.077 ～3.199,P =0.000）;偶尔喝酒（x2=13.633,OR =0.491,95％ CI：0.334 ～0.721,P =0.000）.结论 老年人轻度认知功能损害的影响因素很多,且存在复杂的交互作用.

Objective To explore the related factors to mild cognitive function of community elderly people above 60 years in 4 areas of Hebei Province. Methods Used multi-stage cluster random sampling method to conduct a survey of elderly people above 60 years old in four areas of Hebei Provinice form January to December 2010, which included the assessment of social demographic data and cognitive function （MMSE）. Results Significant differences were found between the 2 groups, which included aging, 70 - 79 years （ X2 = 78. 473, OR = 2. 658, 95% CI：2. 129 - 3.319, P = 0. 000） and above 80 years （ X2 = 252. 168, OR = 8. 555, 95 % CI：6. 356 - 11.516, P = 0. 000） ; years of education, 1 - 6 years （ ~2 = 62. 066, OR = 0. 329, 95% CI：O. 248 - 0. 437, P = 0. 000） , 7 - 12 years （ X2 = 52. 634, OR = 0. 395, 95% CI：O. 305 - 0. 510, P = 0. 000）, above 12 years （ ~2 = 96. 162, OR = 0. 126, 95 % CI： 0. 080 - 0. 200, P = 0. 000 ） ; marriage status, widowed （ ~2 = 51. 710, OR = 2. 263, 95% CI： 1. 804 - 2. 839, P = 0. 000） and other marriage status（x2 = 64. 450, OR = 3. 733, 95% CI： 2. 654 - 5. 251, P = 0. 000 ） ; living alone （ X2 = 27. 765, OR = 2. 135, 95% CI： 1. 601 - 2. 847, P = 0. 000） ; previous occupation, farmers （ X2 = 8.425,0R=1.576, 95%C1：1.157-2.147, P=0.003）, civil servants （X2 =4.148, 0R=0.678, 95%C1： 0. 466 -0. 987, P = 0. 049）, being unemployment （ X2 = 8, 260, OR = 1. 701, 95% CI： 1. 181 - 2. 450, P =0. 004） ; no exercises （X2 =52. 987, OR =2. 315, 95% CI：I. 838 -2. 916, P =0. 000） ; experience of life events, 1 -2 （X2 =8. 220, OR = 1. 412, 95%C1：1. 115 - 1. 790, P=O. 004）, above 3 （X2 =41. 109, OR =2. 545, 95% CI：I. 901 -3. 406, P =0. 000） ; low leisure time activities （X2 =77. 530, OR --2. 577, 95% C1：2. 077 - 3. 199, P = 0. 000） ; occasional drinking （ X2 = 13. 633, OR = 0. 491,95% CI：O. 334 - 0. 721, P = 0. 000 ）. Conclusions The related factors to the mild cognitive function of elderly are various with a variety of interactions.