进展性脑卒中的相关危险因素分析

Analysis of Risk Factors for Stroke in Progresion

目的:探讨影响进展性脑卒中(stroke in progression,SIP)的主要危险因素。方法:回顾分析106例急性脑卒中患者的临床资料,其中SIP患者(SIP组)54例,年龄、性别相匹配的非SIP患者(非SIP组)52例。比较两组患者中有吸烟史、饮酒史、发热以及高血压、高血糖、高血脂患者的比例,分析并比较两组患者颈部血管超声、头颅磁共振血管造影(magnetic resonance angiography,MRA)等检查结果。对各危险因素进行单因素分析。结果:两组患者的年龄、性别差异无统计学意义(P>0.05)。与非SIP组相比,SIP组有高血压、高血糖、高尿酸血症、发热及颈部/颅内外大血管狭窄患者的比例较高(P<0.05);其他因素如冠心病、高脂血症、脑卒中史、吸烟以及饮酒在两组间差异无统计学意义(P>0.05)。结论:高血压、高血糖、高尿酸、发热以及颅内外血管狭窄是SIP的主要危险因素。

Objective：To explore the risk factors for stroke in progression （SIP）. Methods：Clinical datum of 106 acute stroke patients were retrospectively analysed, including 54 SIP patients （SIP group） and the age and sex-matched 52 non SIP patients （non-SIP group）. Smoking, alcohol consumption, blood pressure, blood glucose, blood lipids, body temperature were ob- served in the two groups. Simultaneously, results of vascular ultrasound of the neck and magnetic resonance angiography （MRA） of the head were analyzed. Univariate analysis was carried out. Results： No statistical difference was found in age and sex between the two groups （P^0.05）. The incidences of hypertension, diabetes, hyperuricemia, fever and intraeranial vascu- lar stenosis in head and neck in SIP group were significantly higher than those in non-SIP group （P〈0.05）. The differences were not statistically significant in incidences of coronary heart disease and hyperlipemia disease, history of stroke, as well as smoking, alcohol consumption between the two groups （P〉0.05）. Conclusions： High blood pressure, hyperglycemia, hyperu- ricemia, fever, and intraeranial vascular stenosis are major risk factors for SIP.