摘要
利用循证医学,依据血管紧张素转换酶(ACE)对血压的调节机理,以呋喃丙烯酰三肽(FAPGG)为血管紧张素Ⅰ模拟物,建立了胰蛋白酶模拟体外消化体系和大鼠肝脏混合功能氧化酶(MFO)模拟肝脏代谢体系,测得了未经处理的苋籽水解肽IC50值为1mg/mL,经过体外模拟消化和孵育处理后的苋籽水解肽IC50值为10mg/mL。
According to the angiotensin-converting enzyme（ACE） on blood pressure regulation mechanism,furan acryloyl tripeptide（FAPGG） as it was angiotensinⅠmimetic. It was established in vitro trypsin digestion system and simulated rat liver mixed function oxidase（MFO） analog liver metabolism system. Untreated ACE inhibitory peptides of amaranth IC50valued 1mg/mL,digestion and incubated in vitro after treatment ACE inhibitory peptides IC50 valued 10mg/mL.
出处
《食品工业科技》
CAS
CSCD
北大核心
2014年第8期142-144,156,共4页
Science and Technology of Food Industry
关键词
苋籽
ACE抑制肽
降血压
评价
Amaranth
ACE inhibitory peptides protein
antihypertensive activity
evaluation
