固相微萃取-气相色谱-质谱法测定食品塑料包装袋中6种酞酸酯类化合物

Determination of 6 Phthalate Esters in Food-Packaging Plastic Bags Using Solid-Phase MicroextractionGas Chromatography-Mass Spectrometry

建立固相微萃取-气相色谱-质谱同时测定食品塑料包装袋中6种酞酸酯类化合物的分析方法，并对固相微萃取方式、萃取溶剂、萃取头涂层、萃取温度等参数进行优化。采用85μm PA固相微萃取纤维头、正己烷为萃取溶剂，90℃平衡5min后萃取吸附30min，在250℃进样口解吸5min后供气相色谱-质谱分析。结果表明：该方法的线性范围为0．25-50mg／L，方法检出限为0．049-0．920mg／L，回收率为82．2％-109．0％，相对标准偏差（n=6）为4．0％-12．0％，该方法能很好地富集基体中的目标化合物，满足食品塑料包装袋中多种酞酸酯类化合物的分析要求。

A method based on solid-phase microextraction （SPME） technique followed by gas chromatography-mass spectrometry （GC-MS） was developed for the determination of 6 phthalic acid esters （PAEs） in food-packaging plastic bags. The parameters affecting the partitions of the analytes such as fiber coating, extraction temperature and extraction style were optimized. The final SPME method employed an 85 ℃m polyacrylate （PA）-coating fiber and the extraction solvent used was n-hexane. After equilibration for 5 minutes at 90 ℃, headspace adsorption for 30 minutes was carded out. Then the fiber was introduced into the GC injector port and the extract was desorbed at 250 ℃ for 5 min. The linear range of the method was 0.25-50 mg/L. The detection limits for 6 PAEs were in the range of 0.049--0.920 mg/L, and the recoveries from spiked samples were 82.2%-109.0% with RSDs （n = 6） of 4.0%-12.0%. The method enables enrichment of PAEs from sample matrices and can meet the requirements for the analysis of PAEs in food-packaging plastic bags.