炎性细胞因子在慢性阻塞性肺疾病发病机制中的作用

Role of inflammatory cytokines in the pathogenesis of chronic obstructive pulmonary disease

COPD是威胁人类健康的重要疾病，其分子生物学机制一直以来都是研究的重点，慢性炎症反应是其重要的病因病机，炎症因子在慢性炎症反应其中起到重要作用，主要有白介素家族、肿瘤坏死因子、生长因子、黏附因子、血清脂连素、C反应蛋白等。近年来许多学者对此方面进行了研究，本文就这些因子在COPD炎症反应中的作用进行总结。

Chronic obstructive pulmonary disease （COPD）,is a extremely serious disease and its molecular mechanism has been the focus of the research. Chronic inflammation response is an important pathogenesis. Inflammatory cytokines play an important role in the chronic inflammatory response and they have been studied by many researchers in the past years. This paper is a summary of inflammatory cytokines＇ effects on COPD inflammatory response. Interleukins, tumor necrosis factors,growth factors, adhesion factors,serum adiponectin and C-reactive protein are included in the inflammatory cytokines.