2型糖尿病患者肺结核的临床特点分析

Clinical characteristics of type 2 diabetes patients with pulmonary tuberculosis

目的评价2型糖尿病对肺结核临床特点的影响,以降低感染率,提高临床用药水平。方法回顾性分析2008年10月-2012年10月住院的79例2型糖尿病合并结核感染患者为糖尿病组和同期住院未合并糖尿病的肺结核432例患者为非糖尿病组,比较两组患者入院时临床资料以及炎症因子C-反应蛋白的情况,采用SPSS16.0软件进行χ2检验。结果发生医院感染率糖尿病患者为9.1%、非糖尿病患者为6.0%;糖尿病组的中性粒细胞(0.5×109/L)和C-反应蛋白(17.8mg/L)均高于非糖尿病结核患者,差异有统计学意义(P<0.05)。结论糖尿病对结核患者的部分临床特点有一定的影响,差异有统计学意义。

OBJECTIVE To assess type 2 diabetes on the clinical manifestations in patients with pulmonary tubercu- losis so as to reduce infection rate and improve the clinical medication level. METHODS Totally 79 pulmonary TB patients with type 2 diabetes in the diabetes group and 432 TB patients without type 2 diabetes in the non-diabetic group during the same hospitalization period were selected for retrospective analysis from Oct 2008-Oct 2012. Two groups of patients were compared on admission clinical data and the inflammatory cytokines C-reactive protein. Chi-square test was conducted by SPSS 16.0 software. RESULTS The occurrence rates of nosocomial infection were 9.1 ~ in diabetic patients and 6.0% in non-diabetic patients; the number of neutrophils in diabetic group （0.5χ109/L） and C-reactive protein （17. 8 rag/L） were both higher than those in non-diabetic tuberculosis patients. The difference was significant （P^0.05）. CONCLUSION Diabetes has some impact on the clinical mani- festations of TB patients. The difference is significant.