摘要
目的:了解广西桂中地区中成药不良反应发生情况、特点及规律,促进中成药的合理使用。方法:采用回顾性研究方法,从广西桂中地区药品不良反应监测中心数据库下载2010—2012年本地区上报的不良反应报告表,筛选出中成药不良反应报告表进行分类、统计、分析。结果:共筛选出中成药不良反应1 237例,涉及125种中成药;注射剂是导致不良反应的主要剂型,共1 078例(占87.15%);累及器官和(或)系统主要为皮肤及其附件损害,共718例(占58.04%),其次为全身性损害,共220例(占17.78%)。结论:应加强中成药不良反应的监测,规范中成药药品说明书,正确合理使用中成药,降低不良反应的发生率。
OBJECTIVE：To investigate the occurrence, characteristics and regular patterns of adverse drug reactions （ADRs） induced by Chinese patent medicine in Guangxi Guizhong area so as to promote rational use of Chinese patent medicines. METHODS： By a retrospective method, the ADR reports in Guangxi Guizhong area during 2010-2012 period were downloaded from the database of Guangxi ADR monitoring center, with Chinese patent medicine-induced ADR reports analyzed statistically. RESULTS： A total of 1 237 ADR cases were induced by Chinese patent medicines involving 125 kinds of traditional Chinese medicines, with injections leading the list which caused 1 078 ADR cases（87.15% ）. Damage of skin and its appendages took the lead with 718 cases （58.04%）, followed by systemic lesion of 220 cases（ 17.78% ）. CONCLUSION： It is important to intensify ADR monitoring, standardize package inserts of Chinese patent medicine, and achieve correct and rational use of Chinese patent medicine and reduce the incidence of ADRs.
出处
《中国医院用药评价与分析》
2014年第3期262-264,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
中成药不良反应分析
Chinese patent medicine
Adverse drug reaction
Analysis
