地佐辛联合丙泊酚在无痛人工流产术中的应用研究

Application research of Dezocine combined with Propofol in painless induced abortion

目的研究地佐辛联合丙泊酚用于无痛人工流产术(简称人流术)的有效性及安全性,为临床治疗提供参考。方法将2010年1月至2013年6月禹州市人民医院行无痛人流术的早孕妇女176例,随机分为观察组和对照组,每组各88例。观察组用地佐辛联合丙泊酚麻醉;对照组用芬太尼联合丙泊酚麻醉。监测麻醉前后两组受术者的血压、血氧饱和度、心电图、心率,记录受术者苏醒后下腹疼痛程度,受术者的满意程度,不良反应发生情况。结果与对照组比较,观察组患者镇痛效果好于对照组,满意程度高,不良反应发生率低(P<0.05)。结论地佐辛联合丙泊酚用于无痛人流术可以有效减轻术后疼痛,明显提升受术者的满意程度,降低不良反应发生率,该方法安全有效,值得临床推广应用。

Objective To study the efficacy and safety of dezocine combined with propofol using in painless induced abortion and to provide a reference for the clinical treatment. Methods 176 cases in early pregnancy with painless induced abortion from January 2010 to June 2013 were randomly divided into observation group and control group. The patients in observation group were treated by Dezocine combined with Propofol, the patients in control group were treated by Fentanyl combined with Propofol. Blood pressure, SpO2, electrocardiogram, heart rate of patients were monitored, abdominal pain degree at each time point after surgery, degree of＂ satisfaction, incidence of adverse reactions of patients were recorded. Results Analgesic effect after surgery in the observation group was better than control group, Observation group has higher satisfaction degree and lower incidence of adverse reactions compared with control group （P 〈 0.05）. Conclusion Dezoeine combined with Propofol using in painless induced abortion can reduce postoperative pain effectively , significantly improve satisfaction degree of the patients and decrease the incidence of adverse reactions. The method is safe and effective, and it is valuable for clinical use.