摘要
目的分析阿托伐他汀对不稳定型心绞痛（uA）患者血浆c一反应蛋白和血脂的影响。方法将200例uA患者随机分为治疗组和对照组，每组100例，两组均采用常规治疗，治疗组在此基础上给予阿托伐他汀20mg／d，疗程12周，观察两组研究对象血脂以及炎症因子C-反应蛋白的差异，并比较两组治疗前后血脂和血浆C-反应蛋白的变化。结果与对照组比较，治疗组可明显降低血脂及C-反应蛋白水平，差异有统计学意义（P〈0．01）。结论uA患者早期应用阿托伐他汀治疗可以降低患者血浆CRP的浓度，降低胆固醇、甘油三酯和低密度脂蛋白．减轻炎症反应．稳定动脉粥样硬化斑块。
Objective To analyze the effect of atorvastatin on C-reactive protein and blood lipid levels in patients with unstable angina （UA）. Methods Two hundred patients with unstable angina were randomly divided into treatment group and control group. The patients in the two groups were all given conventional treatment, and the patients in treatment group were given atorvastatin 20 mg/d, the course was 12 weeks. The levels of blood fat and C-reactive protein before and after treatment in the two groups were observed. Results Compared with control group, the levels of blood fat and C-reactive protein re- duced significantly in treatment group （P 〈 0. 01 ）. Conclusions Early administration of atorvastatin can decrease the plasma eoncetration of hs-CRP, TC, TG and LDL-C significantly in patients with unstable angina, relieve the inflammatory reaction and stablize the atheroscleratic plaque.
出处
《中国实用医刊》
2014年第9期19-20,共2页
Chinese Journal of Practical Medicine
