儿童传染性单核细胞增多症112例临床特点分析

Clinical characteristics analysis of infectious mononucleosis in children

目的探讨儿童传染性单核细胞增多症（ira）的临床表现和实验室检查特点。方法收集2011年8月至2013年8月郑州大学第三附属医院收治的112例传染性单核细胞增多症患儿的临床资料，进行回顾性分析。结果本研究7岁以下儿童最多（78％）；眼睑水肿是IM早期较常见的临床表现，发生率高于肝脾脏肿大和皮疹；异形淋巴细胞≥10％患儿仅占56．6％。结论小儿IM临床表现与实验室检查表现复杂，部分患儿临床表现不典型，眼睑水肿与其他典型表现一样对IM具有诊断价值；异形淋巴细胞比例在诊断IM特别是婴幼儿IM的应用价值应该进一步探讨。

Objective To investigate the clinical manifestation and laboratory examination of children＇s infectious mononucleosis （IM）. Methods The clinical data of 112 children with infectious mononucleosis from August 2011 to August 2013 in the third affiliated hospital of Zhengzhou university were retrospe ctively analyzed. Results Among all of the IM children, the incidence of preschool chil- dren was the most（78% ） , eyelid edema was one of the more common clinical manifestation in IM early stage, and the incidence was higher than that of spleen edema and rash. Patients with special-shaped lymphocyte ≥ 10% accounting for only 56. 6%. Conclusions The clinical manifestation and laboratory examination performance in pediatric IM is complex, the clinical manifestations in ratio some cases are a- typical, eyelid edema and other typical performance of IM have diagnostic value; the value of atypical lymphocytes ratio in the diagnosis of IM, especially infants IM, should be further discussed.