气相色谱-串联质谱法检测昆仑雪菊中18种有机磷农药残留量

Determination of Eighteen Pesticide Residues in Coriopsis ticntoria by Gas Chromatography-tandem Mass Spectrometry

为定量分析昆仑雪菊中有机磷类农药的残留，从市场采集雪菊样品，采用气相色谱串联质谱法对新疆昆仑雪菊中18种有机磷农药残留量进行检测。结果表明：在样品采用乙腈提取、固相萃取（SPE）柱净化后，所有农药在15 min 内完全分离并流出；在18种有机磷农药保留时间确定的串联质谱检测条件下，其2种添加浓度的加标回收率在71．2％～93．5％，相对标准偏差（RSD）在2．17％～6．20％。在0．05～1．0 mg/L 质量浓度范围内的线性关系良好（r 2＞0．99）。样品经过检测均未含有农药残留，该方法的灵敏度、精密度和准确度均满足农药残留分析要求，适用于雪菊中的有机磷农药残留的快速筛查与定性、定量分析。

To quantitatively analye organophosphorus pesticides in C. ticntoria, 18 kinds of organophosphorus pesticides in C. ticntoria were detected by Gas chromatography-tandem mass spectrometry.The gas chromatography-tandem mass spectrometry （GC-MS/MS）method was established for analysis of 18 organic phosphorus pesticides in C. ticntoria. The samples were extracted by acetonitrile,and cleaned up by SPE column;Then the extracts were determined with a MS/MS detector based on MRM,All of them were well separated within 15min.When the spiked average recoveries ranged from 71.2% to 93.5%.The RSD ranged from 2.17%~6.20%,The pesticides were of good linearity in the range of 0.05~1.0 mg/L.In the samples no pesticide residues were detected.The method was accurate and sensitive,which was suitable for analysis of various pesticides residues in C.ticntoria.