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长链非编码核糖核酸在心脏发育及心血管疾病中的作用研究进展 被引量：6

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摘要 长链非编码核糖核酸(long noncoding RNA,lncRNA)是一类长度大于200个核苷酸的非编码RNA。研究表明lncRNA能以RNA的形式在多种层面上(表观遗传、转录及转录后水平)调控基因的表达,参与了细胞凋亡、增殖,发育等重要生物学过程。近年来,lncRNA在心血管疾病中的作用获得关注。现将lncRNA在心脏发育及心血管疾病中的作用作一综述。
作者 刘岗 黄晓红
机构地区 北京协和医学院中国医学科学院心血管病研究所阜外心血管病医院特需医疗诊治中心
出处 《中国循环杂志》 CSCD 北大核心 2014年第4期312-314,共3页 Chinese Circulation Journal
基金 国家自然科学基金(基金编号:81241007)
关键词 长链非编码核糖核酸 心脏发育 心血管疾病
分类号 R541 [医药卫生—心血管疾病]
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参考文献27

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同被引文献49

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  • 10Jeon Y, Lee JT. YY1 tethers Xist RNA to the inactive X nucleation center. Cell, 2011, 146:119-133.

引证文献6

二级引证文献15

中国循环杂志
2014年 第4期

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