基于生物矿化的生物壳工程

Biomineralization-based biological shellization

生物矿化是生物体提高自身存活能力的重要手段,可以通过无机非生命体实现对有机生命体的保护和功能化.得益于这些自然现象的启发,我们将生物矿化原理应用于各种生物单元的功能化改造,进一步提出了仿生壳工程概念.经过生物矿化改造后,生物体系可以维持原有生物性质但又被人工材料赋予了新功能,在材料、生物、医学等各个领域有着重要的价值.本文对基于生物矿化的壳工程修饰方法及其应用进行了介绍,并对该领域的研究前景进行了展望.

Biomineralization has been evolved by many organisms to improve their survivals and performance in harsh environment, which demonstrate the importance of inorganic minerals in biological protections and functionalizations. Inspired by these natural phenomena, we proposed biomimetic surface modification and functionalization of organisms by using biomineralization. It followed a new concept of ＂biomimetic shellization engineering＂. Such a material-based strategy can confer living organisms new properties thorough artificial materials without significantly impairing their original functions. The studies have demonstrated that biomineralization holds great promises in materials, biological and medical areas. The methods of biomimetic shellization as well as its applications and perspectives are reviewed in this paper.