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反应性穿通性胶原病1例 被引量:4

Reactive perforating collagenosis:a case report
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摘要 患者女,21岁。下肢红斑、丘疹伴瘙痒1个月,无系统疾病。皮肤科检查:双下肢红斑、丘疹,中心有脐凹,内含角质栓。皮损组织病理示:表皮缺如,下方为坏死胶原纤维穿通表皮。诊断:反应性穿通性胶原病。 A 21-year-old female presented with multiple erythematic papule on the lower limbs for one month.The patient had no history of systemic disease. The lesions were erythematic papules with umbilieation and a central keratin plug. Histopathology showed the epidermis was absent where degenerated collagen fiber come out from epidermis. The diagnosis of reactive perforating collagenosis was made.
出处 《中国麻风皮肤病杂志》 2014年第3期190-191,共2页 China Journal of Leprosy and Skin Diseases
关键词 反应性穿通性胶原病 reactive perforating collagenosis
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参考文献6

  • 1赵辨.中国临床皮肤病学.南京:江苏科学技术出版社,2009.
  • 2Gambichler T, Birkner L, Stticker M, et al. Up-regulation of transforming growth factor-b3 and extracellular matrix proteins in acquired reactive perforating collagenosis. J Am Acad Dermatol, 2009,60 ( 3 ) : 463- 469.
  • 3陈小敏,陈丽芳,史维平,刘金华.获得性反应性穿通性胶原病一例[J].中华皮肤科杂志,2007,40(11):687-687. 被引量:1
  • 4Mii S, Yotsul R, Hayashi R, et al. Acquired Reactive Perfora- ting Collagenosis Successfully Treated with Narrow-band Ultravi- olet B. Acta Derm Venereol,2009,89(5) :530-531.
  • 5Sehgal VN, Verma P, Bhattacharya SN, et al. Familial Reactive Perforating Collagenosis in a Child: Response to Narrow-Band UVB. Pediatric Dermatol,2013,30(6) :762-764.
  • 6Hoque SR, Ameen M, Holden CA. et al. Acquired reactive per- forating collagenosis: four patients with a giant variant treated with allopurinol. Br J Dermatol,2006,154(4) :759-762.

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