金纳多联合高压氧治疗突发性聋的疗效分析

Analysis of curative effect of Ginaton combined with hyperbaric oxygen in the treatment of sudden deafness

目的分析金纳多联合高压氧治疗突发性聋的疗效,并探讨突发性聋的相关发病因素与疗效的关系。方法回顾性总结分析2010年1月至2011年12月在我院诊断并治疗的150例突发性聋患者的一般临床资料并进行疗效评估。结果 1、150例患者发病构成比调查中:女性、中年人、脑力劳动者、很少运动者、一般紧张者、单耳发病者构成比最大。2、治疗疗效为治愈49例,显效30例,有效27例,无效53例,总有效率为62.72%。3、在各因素与突发性聋疗效分析中,纯音听阈图(治疗前听力损失程度和听力曲线类型)、伴随眩晕、发病至就诊时间与突发性聋的疗效有统计学意义(P<0.05),认为上述因素影响突发性聋的疗效。而发病耳侧、伴发高血压、伴发糖尿病、白细胞数值、发病时情况、伴随耳鸣、年龄段与突发性聋的疗效无统计学意义(P>0.05)。结论 1.构成比调查:突发性聋患者中多为中年人以及年轻人多发,并脑力工作者为主。诱发因素中,精神压力大、劳累、睡眠质量差的更易患突发性聋。2.在疗效分析中,①金纳多联合高压氧治疗低频陡降型听力曲线类型的突发性聋患者疗效较好,对于高频下降型、全聋型听力曲线类型的患者疗效较差。②听力分型曲线图、发病至就诊时间是影响突发性聋疗效的因素。

Objective To analyze the curative effect of EGb761 combined with Hyperbaric Oxygen therapy on Sudden hearing loss and to explore relationship between some correlative influencing factors and the therapeutic effect. Methods summarize and analyze the clinical data of 150 Sudden hearing loss patients from Jan 2010 to Dec 2011 in a retrospective way and to evaluate the efficacy. Results 1. In the comparison group, the female,the middle-aged people,the mental work- ers,little movement persons~ general tension persons,single ear unwell＇ person occupies the highest proportion.2, among the 150 patients, 49 cases is cured, 30 cases is markedly effective,27 cases ineffective and53 cases is failed, and the total effec- tive rate was 62.72%.3. Taking all factor into consideration in this study, puretone threshold, Accompanied by dizziness, the length of time between attack and reception of treatment in effect of sudden deafness are of statistical meaning（P〈0.05）, and the author thinks the factors above influent the the prognosis. Factors such as incidence of ear side, associated with hy- pertension, Diabetes mellitus,white blood cell values,the situation of disease, tinnitus, age and the degree of hearing loss have no statistical significance with the curative effect of sudden deafness （P〉0.05）. Conclusion 1. Middle-aged people and younger one have higher risks of sudden deafness. The mental worker is the main group. The main factors are high pressure, tired and lower quality of sleep. 2. Patients with EGb761 combined with Hyperbaric Oxygen treatment on the hearing type of low-frequency steep drop will have a better curative effect. Patients with high-frequency hearing loss or complete deafness hearing curve type of ill have a bad curative effect. 3. The main factor influence the curative effect of sudden hearing loss are hearing type graphs and the length of time between attack and reception of treatment.