椎间盘丸联合腰椎后路植骨融合内固定治疗腰椎间盘突出症的临床研究

Effect of Intervertebral Disc Pill Combined with Lumbar Posterior Bone Graft Fusion and Internal Fixation for Treating Lumbar Intervertebral Disc Herniation

目的:观察椎间盘丸联合腰椎后路植骨融合内固定术治疗腰椎间盘突出症的临床疗效。方法:将60例腰椎间盘出症患者随机分为治疗组(30例)和对照组(30例),且均行腰椎后路髓核摘除植骨融合内固定术,治疗组术后加服椎间盘丸治疗。两组均定期随访(术后1、3、6个月),采用下腰椎JOA评分,X线复查,评估两组神经功能恢复程度、椎间植骨融合率。结果:两组患者术后6个月JOA评分均较术前明显提高,与术前比较,差异有统计学意义(P<0.01),且治疗组术后6个月的JOA评分较对照组有显著提高(P<0.05)。根据JOA分值改善率进行评比,对照组术后优良率为76.7%;治疗组术后优良率为83.4%;两组术后6个月比较治疗组的疗效优于对照组(P<0.05)。两组患者术后植骨融合率均达到100%。结论:腰椎后路髓核摘除植骨融合内固定术治疗腰椎间盘突出症可取得良好效果;椎间盘丸对其临床疗效能够起到强化作用,有助于患者神经功能更好的恢复。

Objective：To explore the clinical effects of intervertebral disc pill （IDP） combined with lumbar posterior bone graft fusion and internal fixation for treating lumbar intervertebral disc herniation （LDH）. Methods： All 60 patients with LDH were randomly divided into two groups. They were all received posterior lumbar nucleus pulposus removed, bone graft fusion, and internal fixation. The treatment group were received IDP additionally. They were all followed up at 1 month, 3 months, and 6 months after operation. The JOA score of the lower lumbar spine was used to evaluate the nerve function; and the lumbar X-ray was used to check the rate of interbody fusion. Results： The JOA score was improved after the operation in both groups （P〈0.01）, and the treatment group was higher than the control group 6 months after opera-tion （P〈0.05）. The excellent rate was 76.7% in control group, and 83.4% in the treatment group. The therapeutic effect in the treatment group was superior to the control group at 6 months after the operation （P〈0.05）. The interbody fusion rate was 100% in both groups. Concluslon：The posterior lumbar nucleus pulposus removed, bone graft fusion, and internal fixation is effective for treating LDH, and DIP can strengthened the therapeutic effect to recovery the nerve func- tion.