静脉输液调配中心环境与自然环境输液调配后不溶性微粒数量对比研究

Comparative study on particulate after infusion deployment under PIVAS and natural environment

目的探讨静脉输液调配中心环境（PIVAS）与自然环境下输液调配不溶性微粒的变化。方法两种环境下分别向5％葡萄糖注射液、0．9％氯化钠注射液中，按1支／次的速度，分1～5次，加入肌苷注射液1～5支，然后检测不溶性微粒并进行比较。结果两种环境下调配的输液检测结果表明，PIVAS环境下所调配的输液中，≥10μm不溶性微粒的污染粒数明显少于自然环境下所调配的输液中的粒数，两项比较有非常显著差异（P〈0．01）；≥25μm不溶性微粒的污染粒数也相对较少。两种环境下加药次数3次以上与加药1次进行比较均有显著差异（P〈0．05）。结论在输液调配过程中，PIVAS环境可明显减少不溶性微粒数量。建议医疗机构应大力提倡PIV．AS环境下进行输液调配。

Objective To explore the influence degree of particulate matter caused after deployment under PIVAS and natural environment and judge the advantages of deploying infusion quality under the two environments. Methods Injected 1 -5 lnosine Injection with 1 vial / time in 1 -5 times to 5% Glucose Injection and 0.9% Sodium Chloride Injection under the two environments. Then detected particulate matter and compared the detection results. Results The deploying infusion detection results under the two environments showed that contamination particulates of ≥10 μm particulate matter of deplo- ying infusion under PIVAS were significantly less than under natural environment and the comparison had significant differ- ence （ P 〈 0.01 ） ; Contamination particulates of ≥25 μm particulate matter were also relatively less than under natural en- vironment. The comparison of dosing frequency more than 3 times and 1 time under the two environment both had signifi- cantly difference （ P 〈 0.05 ）. Conclusion During infusion deploying, PIVAS can obviously promote infusion quality. Therefore,hospitals should advocate infusion deployment under PIVAS and at the same time decreasing dosing frequency during infusion deployment can also promote infusion quality.