从阴虚体质论治干燥综合征

Treating Sj?gren's syndrome from the theory of yin defi ciency constitution

文章首先从形成因素、形成特点、表现特点、指向目标、表达信息、干预目的6方面对干燥综合征阴虚为本的体质与证候进行界定,指出阴虚体质是干燥综合征的易发人群。进而从燥毒、瘀阻病因病理与阴虚体质的内在联系,阐述其阴虚体质为本、燥毒瘀阻为标的病机要点,释解自拟"养阴清燥汤"的组方法度和应用要点,并结合医案进行临床论证,强调从阴虚体质论治干燥综合征的临床意义,将有助于推动"4P"医学模式对慢性疾病防控策略的具体实施,倡导"辨体-辨病-辨证"诊疗模式的综合应用。最后针对目前干燥综合征研究存在的问题,提出从临床流行病学及免疫遗传学角度进行深入研究的思路。

In the paper, we first define the constitution and syndrome of yin deficiency of Sjoegren＇s syndrome, indicate that yin deficiency constitution is prone crowd of Sjoegren＇s syndrome from six aspects： the factors of formation, formation characteristics, performance characteristics, orientation of goal, the information of expression, the purpose of intervention. Then combined with the medical records of clinical demonstration, we explain the key pathogenesis in which yin deficiency is root, dryness toxin and stasis are branch, and interpret application points and group method of self-made Yangyin Qingzao Decoction from the inner connection of etiology and pathology of dryness toxin and stasis and the constitution of yin deficiency. We emphasize the clinical significance of treating Sjoegren＇s syndrome from the theory of yin deficiency constitution, which will help to promote the＇4P＇ medical model implementation for chronic disease control and prevention strategy, to pioneer integrated application of ＇constitution differentiation-disease differentiation-syndrome differentiation＇ model of diagnosis and treatment. In view of the problems currently existing in the study of Sjogren＇s syndrome, we finally propose the method of in-depth study on clinical epidemiology and immunogenetics.