不同分期结肠癌患者行腹腔镜手术的临床效果分析

Clinical Research on Laparoscopic Surgery for Patients with Colonic Cancer in Different Stages

目的:研究不同分期结肠癌患者行腹腔镜手术的临床疗效。方法:选取本院近年收治的结肠癌患者162例为研究对象,其中81例行开腹结肠癌根治术(常规组),另81例行腹腔镜手术(腹腔镜组),比较两组术后复发、远程转移及并发症情况。结果:两组在不同分期上的远处转移、局部复发及1年存活率上比较,差异均无统计学意义(P>0.05);腹腔镜组术后总并发症率明显小于常规组,差异有统计学意义(P<0.05);腹腔镜组Ⅲ期患者术后复发率、转移率及总并发症发生率均明显高于Ⅰ期、Ⅱ期患者,但差异均无统计学意义(P>0.05)。结论:腹腔镜手术治疗结肠癌患者具有高效性和安全性,在手术时机选择上,结肠癌Ⅰ期、Ⅱ期是腹腔镜手术的最佳治疗时机,治疗时应当结合临床分期科学选择术式,进行针对性预后。

Objective：To study the clinical efficacy of laparoscopic surgery for patients with colonic cancer in different stages.Method：162 cases of colonic cancer treated in our hospital were selected as the research objects. The conventional group for 81 cases received laparotomy radical operation for colonic cancer,and the laparoscopic group for 81 cases received laparoscopic operation. The postoperative recurrence,remote transfer and complications of two groups were compared.Result：There were no evident differences for distant metastasis,local recurrence and survival rate greater than 1 year between two groups（P〉0.05）. The incidence rate of complications after operation of the laparoscopic group was evidently less than that of the conventional group,the difference was statistically significant（P〈0.05）. The recurrence rate after operation,transfer rate and incidence rate of complications ofⅢ-stage patients in the laparoscopic group were evidently higher than that ofⅠ-stage patients andⅡ-stage patients,but the differences were no statistically significant（P＆gt;0.05）. Conclusion：Laparoscopic surgery treating patients with colonic cancer is high effective and safe. For the selection of operation opportunity,Ⅰ-stage andⅡ-stage colonic cancer are the best time of laparoscopic surgery. The clinical scientific selection operation modes by stages should be combined for targeted prognosis.