甲氨蝶呤联合米非司酮治疗异位妊娠的疗效分析

Clinical Efficacy of Mifepristone Combined with Methotrexate Treatment of Ectopic Pregnancy

目的:探讨甲氨蝶呤联合米非司酮治疗异位妊娠的临床疗效。方法:对近年来笔者所在医院收治的50例异位妊娠患者的临床资料进行回顾性分析。将50例患者按照治疗方式的不同分为对照组和治疗组,每组25例。治疗组采用甲氨蝶呤联合米非司酮进行治疗,而对照组则单用甲氨蝶呤进行治疗,比较分析两组患者的治疗效果。结果:治疗组25例患者,有效23例,治疗有效率92%;对照组25例患者,有效18例,治疗有效率为72%,两组比较差异有统计学意义(P<0.05)。结论:甲氨蝶呤联合米非司酮治疗异位妊娠的临床疗效较佳,并且治疗成功率更高、不良反应较少,操作简便、安全、可靠,可以保留患者的生育能力,故值得在临床治疗当中进一步推广使用。

Objective：To investigate the clinical efficacy of mifepristone combined with methotrexate treatment of ectopic pregnancy.Method：Clinical data in our hospital 50 cases of ectopic pregnancy in patients treated since in recent years were retrospectively analyzed.According to the different treatment 50 cases were divided into control group and treatment group,25 cases in each group.Treatment group was treated with methotrexate and mifepristone treatment,while control group was to take a single methotrexate treatment.Comparative analysis of the therapeutic effect of two groups.Result：Treatment group,23 cases were effective, the treatment efficiency was 92%;Control group,18 cases were effective,the treatment efficiency was 72%,the difference of two groups was significant（P〈0.05）. Conclusion：The clinical efficacy of mifepristone combined with methotrexate for ectopic pregnancy is better and higher treatment success rates,fewer adverse reactions,simple,safe,reliable,and can keep the patient’s fertility,it is worth in the clinical treatment which further promote the use.