摘要
以鲤鱼肝微粒体为实验体系 ,研究了被五种多环芳烃 ( PAH)化合物菲、9,1 0 -菲醌、芘、1 -羟基芘、苯并芘污染后 ,其芳烃羟化酶 ( AHH)的活性变化 ,发现多环芳烃对 AHH的诱导具有良好的剂量效应关系。 AHH活性升高的大小可以作为监测多环芳烃对水体污染程度的一种生物指标。五种多环芳烃对 AHH诱导能力的大小为 1 -羟基芘 >苯并芘 ;9,1 0 -菲醌 >芘 >菲 ,与其毒性大小相关。
The aryl hydrocarbon hydroxylase(AHH) activity of carp liver microsome induced by five polyaromatic hydrocarbon (PAH) compounds was examined Five tested PAH named as phenanthrene; 9,10 phenananthrenquinone, pyrene, benzo[a]pyrene, 1 hydroxypyrene induced AHH activity to different extent There existed a good dose effect correlation between the AHH induction and aromatic hydrocarbons concentration The AHH activity of fish liver microsome can be used as a biomarker to evaluate the aromatic hydrocarbon contamination in waters The intense of AHH activity induced by five aromatic hydrocarbons which was related to the toxicity chemicals was as following: 1 hydroxypyrene > benzo[a]pyrene; 9,10 phenananthrenquinone > pyrene > phenanthrene
出处
《中国环境监测》
CAS
CSCD
北大核心
2000年第6期8-11,共4页
Environmental Monitoring in China
基金
国家自然科学基金!( 39770 1 52 )
