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降钙素原指导下急性阑尾炎术后抗生素应用研究 被引量:4

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摘要 目的探讨急性阑尾炎术后降钙素原(PCT)指导下抗生素应用的临床价值。方法观察与分析80例急性阑尾炎术后患者抗生素应用结果。其中40例患者(PCT组)在术后第1、3及5天隔天抽血化验PCT及血常规水平,至研究截点。在降钙素原正常(<0.5 ng/ml)停用抗生素。余40例患者依据传统标准停用抗生素。比较两组患者住院时间、感染相关并发症与抗生素应用天数。结果两组术后住院时间和感染并发症发生率差异无统计学意义(P>0.05),抗生素应用天数差异有统计学意义(P<0.01)。结论急性阑尾炎术后PCT指导下抗生素应用要优于传统标准抗生素应用。
出处 《现代实用医学》 2014年第3期325-326,共2页 Modern Practical Medicine
基金 浙江省温州市科技局资助项目(Y20130095)
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  • 1何礼贤.值得研究和借鉴的短程抗菌治疗策略[J].中国抗感染化疗杂志,2005,5(5):318-319. 被引量:20
  • 2陆权.儿童社区获得性肺炎管理指南(试行)(上)[J].中华儿科杂志,2007,45(2):83-90. 被引量:605
  • 3Levy M M, Fink M P, Marshall J C, et al. 2001 SCCM/ESICM/ ACCP/ATS/SIS international sepsis definitions conference [J]. Intensive Care Med, 2003,29 (4) : 530-538.
  • 4Wanner G A, Keel M, Steckholzer U, et al. Relationship between procalcitonin plasma levels and severity of injury, sepsis, organ failure, and mortality in injured patients [J]. Crit Care Med,2000, 28(4) :950-957.
  • 5American Thoracic Society, Infectious Diseases Society. Guidelines for the management of adult with hospital-acquired, ventilatorassociated, and healthcare-associated pneumonia [J]. Am J Respir Crit Care Med, 2005,171 (4) : 388-416.
  • 6Assicot M, Gendrel D, Carsin H, et al. ,High serum procalcitonin concentrations in patients with sepsis and infection [J]. Lancet, 1993, 341 (8844) :515-518.
  • 7Al-Nakeeb S, Clermont G. Procalcitonin testing has the potential to reduce unnecessary antibiotic use in patients with suspected lower respiratory tract infections [ J ]. Crit Care, 2005,9 (3) : E5.
  • 8Bignardi G E, Dhar R, Heycock R, et al. Can procalcitonin testing reduce antibiotic prescribing for respiratory infections [J]? Age Ageing, 2006,35 (6) : 625-626.
  • 9Claeys R, V inken S, Spapen H, et al. Plasma proealcitonin and C- reactive protein in acute septic shock: clinical and biological correlates [J]. Cri/Care Mcd,2002,30(4) :757-762.
  • 10Dandona P, Nix D, Wilson M F, et al. Procalcitonin increase after endotoxin injection in normal subjects [J]. J Clin Endocrinol Metab, 1994,79(9) : 1605-1608.

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  • 1张阳德,张宗久,赵明钢,李坚,刘蔚东.“5.12”汶川大地震伤员气性坏疽的早期诊治[J].中国现代医学杂志,2008,18(23):3464-3467. 被引量:4
  • 2孙青海,方翠琴,李其元,焦次来,王宇翔.实验室检查在诊断小儿急性阑尾炎中的价值[J].华中医学杂志,2005,29(4):291-292. 被引量:10
  • 3Vaziri M, Ehsanipour F,Pazouki A, et al. Evaluation of pro- caleitonin as a biomarker of diagnosis, severity and postopera- tive complications in adult patients with acute appendicitis[J]. Med J Islam Repub Iran, 2014,28.. 50.
  • 4Assarsson J, Korner U,Lundholm K.Evaluation of procaleito- nin as a marker to predict antibiotic response in adult patients with acute appendicitis: a prospective observational study[J]. Surg Infect (Larchmt), 2014, 15(5)I 601-605.
  • 5Yu CW, Juan LL,Wu MH, et al . Systematic review and me- ta-analysis of the diagnostic accuracy of procalcitonin, C-reac- tive protein and white blood cell count for suspected acute ap- pendicitis[J]. Br J Surg, 2013, 100(3): 322-329.
  • 6Wu JY,Chen HC,Lee SH, et al . Diagnostic role of procalci- tonin in patients with suspected appendicitis [J]. World J Surg, 2012,36(8) : 1744-1749.
  • 7Khan AN, Sawan A,Likourezos A, et al. The usefulness of procalcitonin in the diagnosis of appendicitis in children- a pi- lot study[J]. Emerg Med Int, 2012, 2012 317504.
  • 8陈燕清.降钙素原联合C反应蛋白检测在外科腹腔感染中的临床意义[c].2014:昆明医科大学.
  • 9Chandel V,Batt SH,Bhat MY, et al . Procalcitonin as the bi- omarker of inflammation in diagnosis of appendicitis in pediat- ric patients and prevention of unnecessary appendectomies[J]. Indian J Surg, 2011 73(2) : 136-141.
  • 10Kafetzis DA, Vetissariou IM, Nikolaides P, et al . Proealeito- nin as a predictor of severe appendicitis in children[J]. Eur J Clin Microbiol Infect Dis, 2005. 24(7): 484-487.

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