治疗未婚女性解脲支原体感染的临床研究

Clinical study on treatment of Ureaplasma urealyticum infection in unmarried women

目的：探讨治疗未婚女性解脲支原体感染的效果。方法：对202名自愿接受本次调查的未婚（有性生活史）女性进行宫颈分泌物培养及药敏，将检测阳性的109例患者随机分为研究组59例和对照组50例；对照组常规治疗。研究组在常规治疗的基础上加敏感药物局部用药10～14天，治疗后4、12周及6个月随访。结果：研究组6个月后复发2例，复发率18．00％；对照组6个月后复发7例，复发率38．90％，两组比较差异有统计学意义（P〈0．01）。结论：重视并提倡对未婚女性常规进行支原体培养及药敏，选择敏感药物在常规治疗的基础上加局部用药疗效可靠，可明显降低未婚女性解脲支原体感染复发率。

Objective： To explore the effect of treatment on Ureaplasma urealyticum （UU） infection in unmarried women. Meth- ods： Cervical secretion culture and drug sensitive test were conducted among 202 unmarried women （having sexual life history） receiving this investigation voluntarily, 109 patients with positive result were randomly divided into study group （59 patients） and control group （50 patients） . The patients in control group were treated with conventional therapy. The patients in study group were treated with conventional therapy and local application of sensitive drugs for 10 - 14 days. The patients in the two groups were followed up at 4, 12 weeks and 6months after treatment. Results： Two patients relapsed after 6 months in study group, the recurrence rate was 18.00% ; 7 patients relapsed after 6 months in control group, the recurrence rate was 38.90%, there was statistically significant difference between the two groups （P 〈 0. 01 ） . Conclusion ： It is recommended to pay attention to and advocate UU culture and drug sensitive test conventionally for the unmarried women, the curative effect of conventional therapy combined with local application of sensitive drugs is reliable, which can significantly reduce the re- currence rate of UU among unmarried women.