卡尔曼滤波法同时测定安痛定注射液三组份含量

Simultaneous Determination of Three Components in Antongding Injection by Kalman Filtering Method

本文采用卡尔曼滤波法不经分离同时测定安痛定注射液中三组份的含量 ,氨基比林、安替比林、巴比妥的平均回收率和相对标准偏差分别为 99 8% ,0 93% ;99 7% ,0 82 %和 99 7% ,1 5 %。将该法用于测定实际体系 ,与标准法对比 ,经 t检验 (P >0 0 5 ) ,两者无显著差异。

Kalman filtering method was applied to determine three components in antongding injection without separation. The average recovery and relative standard deviation of amidopyrine, phenazone, barbital obtained by Kalman filtering method were 99.8%, 0.93%, 99.7%,0.82%,99.7%,1.5% respectively. It was showed by t-test that there was no significant difference between the results of Kalman filtering method and standard method.