正交法合成对亚硝基苯酚

Synthesis of P-Nitrosophenol Using Orthogonal Method

以苯酚、亚硝酸钠和硫酸为原料 ,在醋酸介质下进行亚硝化反应合成对亚硝基苯酚 ,并通过正交试验法筛选出最佳反应条件。

P-Nitrosophenol was synthesized by nitrosation reaction of phenol with a mixture of sodium nitrite and sulfuric acid in the acetic acid medium,The best reaction conditions were selected through orthogonal method.