广西丁型肝炎病毒感染的血清学调查

SEROEPIDEMIOLOGY STUDY ON HEPATITIS D VIRUS INFECTION IN GUANGXI

应用酶联免疫试验(ELISA)对广西7个地区1086例HBV感染者的血清检测了抗-HD,共发现74例阳性,阳性率为6.81%,其中男性阳性率为7.52%,女性阳性率为5.00%,男女间差异无显著意义(P>0.1).年龄以50岁以上多见(P<0.05).各型肝炎中,慢性活动性肝炎、慢性迁延性肝炎的抗-HD阳性率显著高于HBsAg携带者(P<0.01).另外检测231例血清中的HDAg,阳性10例,阳性率为4.33%.以上表明广西各地区均有不同程度的丁型肝炎病毒感染.

Sera anti-HD were tested by ELISA method in 1 086 HBV infection persons from seven regions in Guangxi.The anti-HD positive rate was 6.81%(male 7.57% and female 5.00%), There was no significant difference (P>0.05) between the male and female groups, but the positive rates in the age groups of fifty and upward were much higher than those under fifty.In the above regions the positive rate of anti-HD in CAH and CPH patients was much higher than that in HBsAg carriers.In addition, HDAg was tested by ELISA in 231 HBV infected persons, ten of which were HDAg positive.The HDAg positive rate was 4.33%.This study showed that there were different degrees of HDV infection in various regions in Guangxi.