帕瑞昔布在骨科术后疼痛患者中的应用

目的观察帕瑞昔布在骨科术后疼痛患者中的应用效果。方法骨科术后疼痛患者60例,随机均分为2组(n=30)。帕瑞昔布组和曲马多组,记录2组患者用药前后VAS评分和不良反应。结果 2组患者用药后VAS评分均显著低于用药前,差异有统计学意义(P<0.05);2组患者用药前VAS评分和用药后VAS评分之间比较,差异无统计学意义。帕瑞昔布组嗜睡发生率显著低于曲马多组,差异有统计学意义(P<0.05),其他不良反应2组发生率相当,差异无统计学意义。结论帕瑞昔布对骨科术后疼痛患者有一定的效果、副作用少。

Objective To observe the effect of parecoxib on the patients underwent postoperation pain.Method Sixty orthopedic patients underwent postoperation pain were divided into two groups： parecoxib group and tramadol group. The patients in the parecoxib group were administered with parecoxib. The patients in the tramadol group were administered with tramadol. The VAS score of before medication and after medication in both groups were recorded. The complication in both groups were recorded.Results The VAS score of after medication were lower than those before medication in both groups（P〈0.05）. The VAS score of before medication and after medication were not signiifcantly different between two groups. The incidence of drowsiness in parecoxib group was lower than it in tramadol group（P〈0.05）. Other complication were not signiifcantly different between two groups.Conclusion Parecoxib is effective for he orthopedic patients underwent postoperation pain and its complication are few.