摘要
目的分析高压氧治疗对腔隙性脑梗死伴有轻度认知功能障碍患者的临床治疗效果及护理措施。方法选择南京军区总医院神经内科2013年1—9月脑梗死伴轻度认知功能障碍患者100例,按随机数字表法分为一般治疗组及对照组,每组50例。2组患者均接受脑卒中常规治疗和护理,治疗组在此基础上加用高压氧治疗2个疗程,使用Moca评分评价2组患者治疗后认知功能的改善情况。结果治疗前治疗组与对照组相比,年龄、性别、教育程度、高血压、糖尿病及Moca评分差异无统计学意义(P>0.05),治疗3个月后,治疗组Moca总分(24.25±2.46 vs.22.72±2.56,P=0.000)及空间与执行功能(3.54±0.85 vs.2.96±0.96)、注意(5.42±0.97vs.4.35±1.42,P=0.001)、语言(1.55±0.78 vs.1.23±0.68,P=0.006)及定向力(5.57±0.72 vs.5.08±1.17,P=0.041)评分明显高于对照组,差异有统计学意义,高压氧治疗无明显不良反应。结论高压氧治疗对脑梗死后认知功能障碍具有治疗作用。
Objective To investigate the influence of hyperbaric oxygenation on mild cognitive function in patients with Lacunar infarction. Methods 100 patients with lacunar infarction and mild cognitive dysfunction were enrolled in Depart- ment Neurology of General Hospital of Nanjing military region from January 2013 to September 2013. The patients were di- vided into hyperbaric oxygenation group and control group. The cognitive function were estimated by Moca scale. Results Age, sex, education, hypertension, diabetes and the Moca score in hyperbaric oxygenation group were similar to those in control subjects （ P 〉 0.05 ）. After three months of treatment, Moca score （24.25 ± 2.46 vs. 22.72 _＋ 2.56, P 〉 0. 001 ） , visual spatial（ 3.54 ± 0.85 vs. 2.96 -＋ 0.96 ）, attention （ 1.55 ± 0.78 vs. 1.23 _＋ 0.68, P = 0. 006 ）, language （ 1.55 ± 0.78 vs. 1.23 ± 0.68,P = 0. 006） and orientation function （ 5.57 ± 0.72 vs. 5.08 ± 1.17, P = 0.04l ） scores were higher in hyperbaric oxygenation group than those of control group, and there were no obvious adverse effect. Conclu- sion Hyperbaric oxygenation had effect on the treatment of cognitive dysfunction in patients with lacunar infarction.
出处
《中华全科医学》
2014年第5期818-819,838,共3页
Chinese Journal of General Practice
