血液制品病毒灭活/去除方法概述

Summary of viral inactivation /removal methods in plasma- derived products

血液制品属于临床上广泛使用的一类生物制品,由于是以人的血液为原料,病毒的安全性问题一直是广为关注的问题。为了提高血液制品的安全性,生产过程中应该对可能存在的病毒进行有效的灭活/去除。本文介绍了血液制品中病毒灭活/去除的方法,并对相关方法的有效性和可靠性进行了评价。

As one kind of biological products, plasma - derived products are widely used in clinical practice. The secur- ity issues of virus has gained more and more attention for the special raw material of plasma. To improve the safety of plasma - derived products, potential virus must be inactivated and removed in manufacturing process. This review described the vi- rus inactivation/removal methods in plasma - derived products, and the validity and reliability of the related methods are e- valuated.