摘要
观察7种内科非甲状腺疾病193例患者血清垂体—甲状腺轴激素水平。结果:低T_3血症者占41.6％,高γT_3血症者占61.2％,低T_4血症占16.3％。病情越重,血清T_3的降低及γT_3升高越明显,同时伴血清T_4浓度的降低。低T_3、T_4血症持续并加重者,提示预后不良,病人多死亡;而治疗后低T_3、T_4血症有所改善者,病情则好转。对10例死亡病例进行尸解发现,处于低T_3、T_4血症的非甲状腺疾病患者,其甲状腺滤泡扩大,充满胶质,腺上皮细胞变扁平。
Serum concentrations of T_3. T_4. TSH and γT_3 were measured in seven groups of 193 pa-
tients with nonthyroidal illnesses. The results showed that low T_3 state was found in 41. 6% of the study groups, while high γT_3 state consisted of 61. 2% and low T_4 state 16. 3%. Actually, the more severe the disease state, the lower the T_3 serum level and the higher the γT_3 serum level. In addition, the concentra-tion of serum T_4 also decreased. A continued depression in serum T_3. T_4 values may indicate poor progno- sis of the patients with nonthyroidal illnesses. However, if following the treatment, the concentrations of serum T_3. T_4 increased, the conditions of the patients improved. Autopsy thyroid examination were per- formed in 10 patients with nonthyroidal illnesses. The thyroid follicles were enlarged and filled of colloid. and the epithelium of the follicles were flattened.
